What is the reason for the repeated failure of embryo implantation?

　　During IVF treatment, after ovulation and egg retrieval, it is the process of waiting nervously for the embryo transfer ‘lottery’. Only successful implantation means that the pregnancy has taken a small step forward, which is the first dialogue and embrace between the baby and the mother.

　　However, not every embryo is able to successfully implant and complete the first step of the ‘battle’. The reason for this is that not every embryo has the potential to develop perfectly, and not every cavity of the mother’s womb is open to embrace the embryo.
　　The Embryo: The Iron Is Harder Than It Looks
　　The quality of the embryo itself
　　Embryo implantation is a ‘tough battle’ for the embryo, and the quality of the embryo itself will affect the success of the implantation.
　　The quality of the embryo itself will affect the success of the fertilisation. A strong fighter will naturally have a better chance of winning than a weak one.
　　In a natural pregnancy, only one dominant follicle grows and ruptures each month, and there is a high chance that a strong egg will be released. IVF, on the other hand, stimulates the ovaries to bring back a group of eggs that would otherwise be rejected by atresia and fertilised in vitro.
　　However, not all of these eggs are ‘strong’, especially in patients with diminished ovarian reserve, where the eggs are of low ‘fitness’, which can affect the quality of the embryo. Similarly, the sperm, as one of the ‘teammates’, also bears some responsibility.
　　Chromosomal Abnormalities in Embryos
　　Abnormalities in the chromosomes of the couple may affect the development of the embryo, causing it to stop growing at a certain stage. In clinical practice, there are many cases of failed pregnancies due to chromosomal abnormalities in embryos.
　　These chromosomally abnormal embryos sometimes appear to have normal cell size, divide at a normal rate and are classified as good grade 1 or 2 embryos.
　　However, there is no hiding the defects, especially in older patients with a history of ovarian hypoplasia and ovulation disorders.
　　Therefore, in older patients with repeated implantation failures and recurrent spontaneous miscarriages, screening with pre-implantation genetic screening PGS may be considered to select embryos with normal chromosomes for transfer.
　　Zona pellucida related
　　The quality of the embryo itself is passable, and the thick zona pellucida becomes a barrier when it looks like it is about to implant.
　　The zona pellucida, which surrounds the egg, is used to protect the egg and embryo before fertilisation and before the embryo is hatched and deposited in the womb, but when this ‘protective barrier’ is too thick and too hard, it may cause the embryo to fail to be deposited in the womb.
　　With the help of embryo assisted hatching, the zona pellucida can be thinned to reduce the resistance of the embryo to hatching!
　　The implantation is a bonding process in which both the mother and the child are prepared and co-operating with each other. If you think of the above embryonic causes as the problems of the ‘child’ side, the following are the causes of the mother.
　　Avoid eating bananas, papaya, crabs and other foods that may prompt the embryo to atrophy, as much as possible to eat more green fibre-rich vegetables to plant anti-constipation.
　　8, the surrogate mother if pregnant, transplantation of the fourteenth day of blood results is the HCG is about how much is normal?
　　Generally if the pregnancy test day blood HCG5IU / L need to be based on specific values and clinical to determine whether the pregnancy, HCG values and surrogate mother gestational number of fetuses also have a certain correlation.
　　9, the 11th day of transplantation, a little sneezing, runny nose, no headache and fever, will it affect the implantation?
　　11 days after the transplantation has passed the embryo’s implantation period, will not affect the implantation, if the cold is more serious, it is recommended to consult a specialist in a timely manner, and when consulting a doctor, explain that you may be pregnant.
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